Drug

Zyprexa

Explanation / definition

Zyprexa® belongs to the group of atypical neuroleptics. In addition to a good antipsychotic effect, which is particularly used in therapy for mania, it has a relatively low spectrum of side effects.

Read more too: Zyprexa® Velotabs

Trade names

Zyprexa®, Zyprexa® Velo Tabs

Chemical name

2-methyl-4- (4-methyl-1-piperazinyl) -10H-thieno [2,3-b] [1,5] benzodiazepines

Chemical formula: C17H20N4S6-2½H2O

Active ingredient

Olanzapine

application areas

Zyprexa® is used as drug therapy for various psychiatric illnesses.
Areas of application are:

schizophrenia
mania
Bipolar Disorders (Prophylaxis)
Borderline disorder
delusional depression

Dosage form

Tablets / film-coated tablets
Ampoules

effect

Antipsychotics are drugs that focus on treating psychotic symptoms. The main mechanism lies in the reduction in the activity of the neurotransmitter dopamine brain.

For those interested: Primarily, olanzapine blocks 5-HT2, D1-5 and mACh receptors

dosage

Zyprexa® is available as a tablet, as an orodispersible tablet and as an IM. Ampoule.

Tablets are available in doses of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg and 20 mg.

Orodispersible tablets are available in doses of 5 mg, 10 mg, 15 mg and 20 mg.

Ampoules are available in a dosage of 10 mg

side effect

Only those are listed very frequent (> 10%) to frequent (1-10%) Side effects; Occasional, rare or very rare side effects are not listed !:

Increasing appetite with weight gain (obesity) is the most common NW. The weight gain is usually limited and usually does not lead to obesity.
Increase in blood sugar level (diabetes mellitus)
dizziness
Dry mouth
Constipation (constipation)
Temporary increase in liver values (transaminases)
Rare: extrapyramidal disorders
You can find more about this side effect under our topic Extrapyramidal Syndromes
Rare: leukopenia (drop in white blood cells)
Rare: thrombopenia (drop in blood platelets)

Please also read our article on this Zyprexa® side effects.

interaction

Of the Dismantling the drug will both from smoking as well as through accelerated simultaneous intake of carbamazepine. By taking Fluvoxamine can breakdown the drug slowed down become.

Contraindication

Not recommended the use of Zyprexa® in patients with:

Narrow-angle glaucoma (glaucoma = glaucoma)
Obesity (overweight)
Parkinson's disease
Liver disorders
dementia

price

Since there is always talk of cost pressure in the healthcare sector, we believe it is important to also find out prices for drugs (prices are exemplary and not recommended):

Zyprexa® 2.5 mg 28 film tablets (N2) € 65.45

Zyprexa® 15 mg 28 film tablets (N2) € 258.47

Zyprexa® VeloTab 5 mg 28 film tablets (N2) € 92.41

Zyprexa® VeloTab 20 mg 28 film tablets (N2) € 300.01